Dysphagia optimised imrt

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August undefined, 2024

WebOct 6, 2016 · The aim of Dysphagia/Aspiration at risk structures (DARS) trial is to determine whether reducing the dose to the pharyngeal constrictors with dysphagia-optimised …

Dysphagia-optimised Intensity-modulated Radiotherapy …

WebJun 1, 2024 · A new optimised intensity-modulated radiation therapy (IMRT) pioneered at The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, London, has been shown to spare head and neck cancer patients’ adverse life-long side effects post treatment. The initial results from the Dysphagia-Aspiration Related Structures (DARS) … WebFeb 11, 2024 · Recent evidence suggests that reducing radiotherapy dose delivered to specific anatomical swallowing structures [Swallowing Organs at Risk (SWOARs)] may improve swallowing outcomes post-treatment for patients with head and neck cancer. However, for those patients with tumours of the oropharynx, which typically directly … incastro blocks

Full article: Swallowing sparing intensity modulated radiotherapy ...

WebIMRT had a statistically significant advantage over 3D CRT, in terms of V30 (p=0.051), V50 (p=0.002), V60 (p=0.002), and D80 (p=0.023) for the swallowing structures taken together. ... Further prospective studies are required to confirm these findings. Dysphagia-optimised IMRT is needed to improve swallowing status and quality of life in these ... WebThis study examined knowledge and practices of speech pathologists (SPs) and radiation therapists (RTs) regarding plan optimisation for head and neck cancer patients, and the potential impacts on swallowing function. This study examined knowledge and practices of speech pathologists (SPs) and radiation therapists (RTs) regarding plan optimisation for … WebJan 27, 2024 · But half have a modified type of IMRT (called dysphagia optimised IMRT or Do-IMRT). This is to reduce the radiation dose to the muscles that control swallowing. The aim of the study is to compare the people having the Do-IMRT with those having standard IMRT treatment. This is to find out if modifying the IMRT will improve swallowing after ... in-600 hasler

DARS: a phase III randomised multicentre study of

Optimising Radiation Therapy Dose to the Swallowing Organs

Webingly, there is a focus to establish dysphagia-optimised IMRT (Do-IMRT) strategies [18], which could translate into improved long-term symptom burden outcomes for pharyngeal cancer patients by reducing dose to critical swallowing structures. Reﬁnements to existing technology, in the form of arc-based IMRT and adaptive radiotherapy, Websparing strategies. The aim of Dysphagia/Aspiration at risk structures (DARS) trial is to determine whether reducing the dose to the pharyngeal constrictors with dysphagia-optimised intensity- modulated radiotherapy (Do-IMRT) will lead to an improvement in long- term swallowing function without having any detrimental impact on disease- incastrati serie downloadWebOct 26, 2024 · Swallowing difficulty is a significant side effect for people who have been treated with radiation for head and neck cancer (HNC) [1,2]. Dysphagia-optimised intensity modulated radiotherapy (DO-IMRT) has been shown to reduce dysphagia within a multicentre randomised controlled trial (RCT) by reducing dose to pharyngeal constrictor … in-660a

"WebDec 1, 2024 · Dysphagia-optimised IMRT resulted in a significantly higher mean MDADI score at 12 months post-radiotherapy (78 versus 70; P = 0.02) with no apparent detriment to local control [21, 22]. Studies such as PARSPORT and DARS constitute a structured, evidence-based approach to the introduction of new radiotherapy technology and … " - Dysphagia optimised imrt

Dysphagia optimised imrt

Modified intensity modulated radiotherapy reduces dysphagia in …

WebJul 15, 2024 · Christopher Nutting, MD, joint head of the Division of Radiotherapy and Imaging at The Institute of Cancer Research and consultant clinical oncologist at The Royal Marsden, discusses the results of a randomized phase 3 trial using dysphagia-optimized intensity modulated radiotherapy (Do-IMRT) versus standard IMRT (S-IMRT) in patients … WebOct 26, 2024 · This study aimed to assess the impact of the margin applied to the clinical target volume, to create the planning target volume, on plan quality of a novel dysphagia …

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WebNov 1, 2015 · In this review, we discuss the swallowing structures responsible for functional impairment, analyse the studies that have explored the dose–response relationship between these critical structures and late dysphagia, and consider the merits of reported dysphagia-optimised IMRT (Do-IMRT) approaches, thus far. WebJun 8, 2024 · DO-IMRT, which has been pioneered by researchers from The Royal Marsden Hospital and The Institute of Cancer Research, London, is optimised to reduce the risk …

WebThe following are examples of nursing diagnoses that could be used when caring for a patient with dysphagia: impaired swallowing. risk for aspiration. diarrhea related to … WebMar 17, 2024 · PDF On Mar 17, 2024, Jane Dunton and others published Early swallow outcomes for patients treated with dysphagia - optimised IMRT for oropharyngeal …

WebDec 1, 2004 · Purpose To identify the anatomic structures whose damage or malfunction cause late dysphagia and aspiration after intensive chemotherapy and radiotherapy (RT) for head-and-neck cancer, and to explore whether they can be spared by intensity-modulated RT (IMRT) without compromising target RT. WebMay 20, 2024 · A multi-centre randomised phase 3 trial investigated dysphagia-optimised IMRT (DO-IMRT) to spare DARS for 112 patients with oropharyngeal and …

WebOct 6, 2016 · The aim of Dysphagia/Aspiration at risk structures (DARS) trial is to determine whether reducing the dose to the pharyngeal constrictors with dysphagia-optimised …

WebMar 18, 2024 · Petkar I, Rooney K, Roe JWG, et al. DARs: a phase III randomised multicentre study of dysphagia-optimised intensity modulated radiotherapy (do-IMRT) versus standard intensity-modulated radiotherapy (S-IMRT) in head and neck cancer. BMC Cancer. 2016;16:1–10. Article Google Scholar incastrati youtubeWebSep 9, 2024 · DARS (ISRCTN:25458988) tested if using DO-IMRT to reduce RT dose to the dysphagia/aspiration related structures (DARS) improved swallowing function compared to S-IMRT. Materials and Methods Patients with T1-4, N0-3, M0 OPC/HPC were randomised 1:1 to S-IMRT (65 Gray (Gy)/30 fractions (f) to primary & nodal tumour; 54 Gy/ 30f to … in-65 instructionsWebJun 14, 2024 · Purpose Dysphagia is one of the most important treatment-related side effects in head and neck cancer (HNC), as it can lead to severe life-threating complications such as aspiration pneumonia and malnutrition. Intensity-modulated radiotherapy (IMRT) could reduce swallowing dysfunction by producing a concave dose distribution and … in-65 death 08/06/2022WebJan 1, 2024 · The long-term swallowing outcomes of this novel technique were only slightly worse compared to baseline, suggesting potential functional improvements aimed at reducing dysphagia. A phase III randomised multicenter study [27] of dysphagia-optimised IMRT versus standard IMRT in HNC is currently in progress. The study aims … incat 050WebThe results of the DARS study by Nutting et al. clarified the advantage of limiting the mean doses to key swallowing structures like the pharyngeal constrictors with a significant … incat careersWebingly, there is a focus to establish dysphagia-optimised IMRT (Do-IMRT) strategies [18], which could translate into improved long-term symptom burden outcomes for pharyngeal … incat belroseWebJul 1, 2024 · Increasingly, there is a focus to establish dysphagia-optimised IMRT (Do-IMRT) strategies [18], which could translate into improved long-term symptom burden … incat abn