High fat diet induced diabetes in rats
WebDiabetic nephropathy (DN) exacerbates renal tissue damage and is a major cause of end-stage renal disease. Reactive oxygen species play a vital role in hyperglycemia-induced … Web16 de mar. de 2024 · This study investigated its antioxidative strength and protective effects on organs in high-fat diet (HFD)-induced rodents. Rats were fed HFD for 6 weeks to induce obesity, followed by 10 and 50 mg/kg of geraniin supplementation for 4 weeks to assess its protective potential.
High fat diet induced diabetes in rats
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Web10 de dez. de 2012 · Another group of 90 rats were administered a high-fat and high-sugar diet for 4 weeks (food composition: 32% carbohydrate, 28% fat, 17% protein and 23% other) to induce insulin resistance ( Table I ). Following this, 25 mg/kg STZ dissolved in CASC buffer (Sigma-Aldrich, St. Louis, MO, USA) was injected intraperitoneally. Web5 de jun. de 2008 · Many studies have reported that the rats fed with high-fat diet (HFD) develop insulin resistance but not frank hyperglycemia or diabetes [ 5 – 7 ]. It is suggested that the HFD might be a better way to initiate the insulin resistance which is one of the important features of type 2 diabetes.
Web27 de fev. de 2013 · This study has evaluated the effect of naringin on diet-induced obesity and cardiovascular dysfunction in high carbohydrate, high fat-fed rats. These rats developed increased body weight, glucose intolerance, increased plasma lipid concentrations, hypertension, left ventricular hypertrophy and fibrosis, liver inflammation … Web21 de mar. de 2024 · Our objective was to establish a diabetes mellitus type 2 (DM2) model in rats using a high-fat diet and streptozotocin (HF-STZ). Male Wistar rats (240-250g) …
WebMimosa pudica Linn. (Mimosaceae) has been traditionally used for the management of type 2 diabetes mellitus (T2DM) in India. The present study evaluates the therapeutic efficacy … Web10 de jul. de 2024 · Wistar rats were fed with a high-fat diet for 8 weeks followed by a one-time injection of 25 or 35 mg/kg streptozotocin to induce type 2 diabetes. Then the diabetic rats were fed with regular diet/high-fat diet for 4 weeks. Changes in biochemical parameters were monitored during the 4 weeks. Results
Web21 de ago. de 2015 · A high-fat diet and multiple low doses of streptozotocin were used to develop an improved and more stable type 2 diabetic rat model from which to acquire …
Web1 de mar. de 2024 · The rats were fed with high-fat diet (HFD) for 4 weeks, which included 66% conventional rat feed, 30% coconut oil, 3% cholesterol, ... Pari L., Chandramohan … dark red purple hairhttp://article.sapub.org/10.5923.j.diabetes.20130203.03.html bishop porter memphis tnWeb11 de jan. de 2024 · For instance, a high fructose diet is often conjugated with a high fat diet (HF/HF) to induce T2DM in rodents 17, 18, 19. However, this model refers only to the early stage of T2DM... dark red powerpoint templatesWeb12 de out. de 2024 · Rats were assigned to one of three groups: a control group fed a regular chow diet, a high‐fat diet group (HFD) and a diabetic group (DM2), with both of … bishop porter taylorWeb11 de abr. de 2024 · Introduction. Nonalcoholic fatty liver disease (NAFLD), a common chronic liver disease, is characterized by hepatic fat accumulation without drinking alcohol, which may change into steatohepatitis, cirrhosis, and hepatocellular carcinoma (Duan et al. Citation 2012; Powell et al. Citation 2024).Increasing evidence reveals that obesity and … dark red purple nail polishWebWe hypothesized that a high-fat diet would accelerate the induction of diabetes in this model. The SDT rats were divided into 2 groups, which were fed a high-fat diet or … bishop porter memphisWeb24 de set. de 2013 · Rats were fed a high-fat diet for three weeks, with a single intraperitoneal injection of STZ of either 15, 20, 25 or 30 mg/kg body weight after two weeks. Our results showed that inducing type 2 diabetes, using a combination of high-fat feeding with a low dose of STZ, mimics the human condition. dark red rash on feet